Description
Extract high-quality nucleic acids with less hands-on time
The Maxwell® RSC Instrument is a compact, automated nucleic acid purification platform that processes up to 16 samples simultaneously. Using prefilled cartridges and preprogrammed methods, the Maxwell® RSC offers consistent, reliable DNA or RNA extraction in 25–60 minutes, depending upon sample type. The intuitive graphical interface makes the instrument easy to use, and the integrated Quantus™ Fluorometer lets you collect purification and quantification data in one report.
Francis Crick Institute Case Study:
It saves me in total about 40 minutes per 12 samples, and I do 4 runs per day, so that is almost half a day.
Yan Tsou, Laboratory Research Scientist
Anthony Nolan Research Institute Case Study:
It really is the workhorse of our lab in terms of DNA extraction… allowing us to process multiple samples at once with minimal hands-on time.
Thomas Turner, Senior Post Doctoral Research Scientist

Touch the screen to start the process
The intuitive touch screen interface lets you easily set up your DNA or RNA extraction run. And the advanced administrator functions let you control required sample information and report archiving options.

Prepare the sample cartridges
Place prepared cartridges in the Maxwell® RSC. Press “Start” to purify 1–16 samples using the selected kit’s preprogrammed method. New kit methods are easy to install to expand your instrument capabilities.

Quantitate your purified sample
Complete your nucleic acid purification workflow with highly sensitive and specific fluorescence-based nucleic acid quantification using the Quantus™ Fluorometer with a simple add-and-read format, and receive all your sample data in one report. Easily archive your run reports and export the data for your lab notebook.
The Quantus™ Fluorometer is a dual-channel fluorometer that provides highly sensitive fluorescent detection in a compact, simple-to-use instrument. When used with the preprogrammed settings for Promega QuantiFluor® Dye Systems (QuantiFluor® dsDNA, RNA and ssDNA Systems), the Quantus™ Fluorometer can quickly quantitate nucleic acids. The sensitivity and broad dynamic range of the Quantus™ Fluorometer and QuantiFluor® Dyes allow you to complement your absorbance-based methods and quantify your target molecule over a wider range of concentrations.
The Quantus™ Fluorometer is equipped with two fluorescence channels for nucleic acid and protein quantitation:
Blue fluorescence channel:
Excitation 495nm shortpass (wavelengths up to 495nm), emission 510–580nm.
Red fluorescence channel:
Excitation 640nm shortpass (wavelengths up to 640nm), emission 660–720nm.
Quantitate Even Low-Level DNA Samples Accurately
The sensitivity and broad dynamic range of the Quantus™ Fluorometer and QuantiFluor® Dyes allow you to complement your absorbance-based methods and quantify your target molecule over a wider range of concentrations.
DNA Extraction
DNA purified with the Maxwell® RSC System is compatible with a wide range of downstream applications such as Sanger and next generation sequencing, arrays and digital PCR.
Maxwell® RSC Whole Blood DNA Kit »
Extracts DNA from larger sample sizes (up to 500µl) of whole blood without preprocessing
Maxwell® RSC Blood DNA Kit »
Extracts higher yields of DNA from up to 300µl of whole blood following Proteinase K treatment
Maxwell® RSC Buffy Coat DNA »
Extracts DNA from buffy coat from blood
Maxwell® RSC Buccal Swab DNA Kit »
Extracts DNA from buccal swab
Maxwell® RSC Fecal Microbiome DNA Kit »
Extracts DNA from human and mammalian feces.
Maxwell® RSC Cultured Cells DNA Kit »
Extracts DNA from up to 5×10⁶ mammalian tissue culture cells and 2×10⁹ bacterial cells
Maxwell® RSC Cell DNA Purification Kit »
Extracts DNA from samples containing less than 10,000 cells such as amniotic fluid, cerebral spinal fluid and cell supernatants
Maxwell® RSC DNA FFPE Kit »
Extracts DNA from formalin-fixed paraffin embedded (FFPE) tissue sections
Maxwell® FFPE Plus LEV DNA Purification Kits »
Extracts DNA from FFPE samples with comparable performance to the Maxwell® 16 DNA FFPE LEV Plus Kit
Maxwell® RSC Tissue DNA Kit »
Extracts DNA from 50mg of tissue
Maxwell® RSC Plant DNA Kit »
Extracts DNA from a range of plant sample types including soybean, corn and Arabidopsis
Maxwell® RSC PureFood GMO and Authentication Kit »
Extracts DNA from a wide range of food sample types including soybean, corn, canola, fish, beef and pork
Maxwell® RSC PureFood Pathogen Kit »
Extracts bacterial DNA from a wide range of food sample types for use in NGS, serotyping and identification of spoilage organisms
Maxwell® RSC Stabilized Saliva DNA Kit »
Extracts DNA from stabilized saliva tubes
Maxwell® RSC ccfDNA Plasma Kit »
Extracts ccfDNA from plasma
Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples
RNA Extraction
RNA purified with the Maxwell® RSC System is compatible with downstream applications, such as RT-PCR.
Maxwell® RSC simplyRNA Blood Kit »
Purifies total RNA from 2.5ml of fresh whole blood
Maxwell® RSC simplyRNA Cells Kit »
Purifies total RNA from fresh or frozen cells
Maxwell® RSC RNA FFPE Kit »
Extracts RNA from formalin-fixed paraffin embedded (FFPE) tissue sections
Maxwell® RSC Plant RNA Kit »
Extracts RNA from a range of plant sample types including soybean, corn and Arabidopsis
Maxwell® RSC simplyRNA Tissue Kit »
Purifies total RNA from up to 20mg of tissue
Maxwell® RSC miRNA Tissue Kit »
Purifies total RNA, including miRNA, from mammalian tissue samples
Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples
Maxwell® RSC miRNA Plasma and Serum Kit »
Purifies high-quality, amplifiable miRNA from plasma, serum or enriched exosomes
Processing Time: 25–60 minutes
Number of Samples: Up to 16
Weight: 24.2lb (11kg)
Dimensions: 13W × 13.6D × 11.8H inches(330.2 × 345.2 × 299.7mm)
Power Requirements: 100–240VAC,50/60Hz, 2.5A
Fuse: 250VAC, 2.5A, low breaking capacity, time-lag fuse (AC250V, T2.5AL, 5 × 20mm)
UV Bulb: Average lifetime approximately 6,000 hours, length 135.9mm, diameter 16mm, 4W, 0.17A current, 29V, spectral peak F 253.7, UV output 0.9W


A. Maxwell® RSC Instrument
B. Tablet PC preloaded with Maxwell® RSC Application Software
C. USB Cable – Maxwell® RSC Instrument to Tablet PC
D. Power Cable for Maxwell® RSC Instrument
E. Power Cords for Tablet PC
F. Maxwell® RSC/CSC Deck Tray
G. Quantus™ Fluorometer and accessories
H. Tablet PC Holder
I. USB cable – Maxwell® RSC Instrument to Quantus™ Fluorometer
UV Bulb (installed)
Quick Start Guide
Setup Guide
Accessories Available Separately
Additional deck trays, plungers and an optional bar code reader are available for purchase separately.
Protocols
Complete Protocol